4/13/2023 0 Comments Adrenal insufficiency treatment![]() Adrenal destruction may occur in the absence of CPAI history and may be due to bilateral massive adrenal hemorrhage (BMAH) as seen in Waterhouse-Friderichsen syndrome. It can also be caused by medications that reduce steroid metabolism for patients with tuberculosis, opportunistic mycoses and viral infections in immunocompromised patients and adrenal metastases. ![]() Adrenal destruction may be associated with autoimmune adrenalitis (Addison disease), isolated or in the context of autoimmune polyendocrinopathy type 1, 2 or 4. ![]() AAI may result from an acute exacerbation of chronic primary adrenal insufficiency (CPAI). A precipitating illness (severe infection, acute myocardial infarction, stroke), surgery without adrenal support, pregnancy, any acute or chronic disease, or acute trauma are other potential causes of an acute adrenal crisis. Steroid withdrawal is the most common cause of AAI in patients with chronic adrenal insufficiency. If untreated, shock and bilateral adrenal hemorrhage can rapidly lead to death. ![]() ![]() Asymptomatic hypoglycemia, Hypoglycemic seizures or symptoms of dehydration are common manifestations seen in children. The initial presentation may be non specific and may be limited to abdominal pain, nausea, vomiting, weight loss, tachycardia, and fever. Acute adrenal insufficiency (AAI) exact prevalence is unknown. ![]()
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